Abstract: Hospitals, as complex and specialized architectural structures, have a direct impact on the efficiency of medical services and the sustainability of resource utilization through the design of their energy systems. This paper delves into the energy demand patterns of different areas within hospitals during various time periods and proposes a strategy for the design and optimization of hospital energy systems based on time-based zoning. Through a detailed analysis of a specific case involving the heating system, the paper reveals the potential energy wastage and unnecessary operational cost escalation resulting from the conventional one-size-fits-all energy supply approach. To address this issue, the concept of time-based zoning is introduced with the aim of providing customized energy supply to different areas within the hospital. The objective is to significantly enhance overall energy utilization efficiency while concurrently reducing operational costs, thus achieving goals related to environmental conservation and energy efficiency.